Nerve: Rethink Pain

An Ambispective, Multicenter, Registry Study of Patients Considering Surgical Treatment for Chronic Neuropathic Pain 

Rethink Pain™ Registry

This registry is designed to assess the treatment path of patients presenting for surgical intervention due to chronic neuropathic pain and to evaluate the overall effectiveness of surgical treatment for such pain. Data on the mechanism(s) of injury, non-surgical treatment courses, surgical treatments, concomitant treatments and peri/post-surgical outcomes will be collected and reported.

This registry is designed to be a multi-institutional collaborative effort to better understand how patients with chronic neuropathic pain are treated.

Are you eligible to participate in this study?

Inclusion Criteria:

  • Age >18
  • Planning surgical treatment for nerve pain from a neuroma in the upper or lower extremity (some patients might be enrolled if not planning surgical treatment –please discuss with your physician)
  • Have a diagnosis of nerve pain from a symptomatic neuroma as defined by a participating surgeon
  • Be willing to participate as a study subject for 8 visits over 36 months
  • Be experiencing pain at a higher than average level and for greater than 3 months.

Exclusion criteria:

  • Brachial Plexus, Supraclavicular nerve (neck), or axillary nerve (shoulder) neuromas
  • Prior neuroma surgery for the same nerve
  • Participation in other clinical trials
  • Be taking medications that contribute to nerve pain
  • Have carpal tunnel, or other compression nerve injuries
  • History of kidney or liver dysfunction
  • History of substance abuse

What do you need to know?

Participation in research is entirely voluntary. If you think you qualify to be part of this study, ask your doctor about participation.

Contact us if you are eligible and interested in this study

Please contact Lexie Reissaus, Clinical Research Manager at

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